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VariSafe™ RNA Controls


Looking for safe assay controls for highly infectious viruses or foreign animal diseases?

Varizymes offers a selection of VariSafe RNAs – nuclease-resistant, single-stranded RNAs, suitable as process controls for RNA extraction from various sample matrices. These specially-engineered, non-infectious, MS2 phage-like particles protect their contents from degradation by nucleases and can package sequences of up to 1.5 kb from viruses such as SARS-CoV-2, foot-and-mouth disease virus, and human immunodeficiency virus. We also offer made-to-order VariSafe RNAs (contact for details).

Consider using VariSafe RNA controls to facilitate molecular diagnostic assay development using Varizymes' Torch technology.

For more details on the target sequences, click here.

*These products are intended for research use only, not for therapeutic or diagnostic purposes in humans or animals. The safety and efficacy of these products in diagnostic or other clinical uses has not been established.

For bulk orders, Contact Us

Amount: Between 1E6 or 1E10 copies (cp),
Concentration: Between 1E7 or 1E10 cp/mL, repectively, Volume: 0.1 and 1 mL,

Lysis: 65° C for 5 minutes in the RT step or by standard RNA extraction

Buffer composition: 10 mM Tris HCl, 100 mM NaCl, 1 mM MgCl2, 0.1% gelatin, pH 7.0 (alternate buffers available as custom orders)

Storage temperature: 4 °C


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Take your research and development to the next level by leveraging our unmatched expertise and passion for enzymes. We look forward to being your trusted partner for current and future enzyme and molecular biology needs. Contact us today.

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Scientific Spotlight - Selection of Varizymes' Team


Yogesh Chander, PhD

Chief Technology Officer

3,800+ citations. See Google Scholar

Alyssa Hassinger

Research Scientist

190+ citations
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