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RNase Inhibitor


RNase Inhibitor (RI) is a 50 kDa protein that specifically inhibits RNases A, B, and C by binding noncovalently in a 1:1 ratio at high affinity. It can be used in isothermal amplification and molecular diagnostic assays, cDNA synthesis, and other applications where RNA stability is important. It is not effective against RNase1, T1, S1 Nuclease, or RNase H. It has no inhibition of polymerase activity when used with Taq DNA polymerase, AMV, M-MuLV, HIV reverse transcriptases or phage RNA polymerases. An animal-free version of this product is available as a custom order.

*These products are intended for research use only, not for therapeutic or diagnostic purposes in humans or animals. The safety and efficacy of these products in diagnostic or other clinical uses has not been established.

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Stored in 10 mM Tris-HCl, 50 mM KCl, 8 mM DTT, 50% glycerol pH=7.5

To prevent the release of ribonuclease from RNase Inhibitor, temperatures
greater than 50 °C and high concentrations of denaturing reagents such
as urea should be avoided.


Options Amplified
Specificity Sensitivity Multiplexity

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Scientific Spotlight - Selection of Varizymes' Team


Yogesh Chander, PhD

Chief Technology Officer

3,800+ citations. See Google Scholar

Alyssa Hassinger

Research Scientist

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