About Us


We are a B2B custom enzyme provider with decades of expertise in molecular biology, genome mining and protein purification.

Our product catalog features a wide range of proprietary enzymes, from advanced molecular amplification, to assay development and detection technologies... and that's only the beginning of what we have to offer!

We perform the difficult, time-consuming labor of perfecting each and every enzyme, to order, then it's packaged, labeled and shipped to you or your customer at a price point that can't be beat.

We make the hard stuff easy.

Publications


Keown RA, Dums JT, Brumm PJ, MacDonald J, Mead DA, Ferrell BD, Moore RM, Harrison AO, Polson SW, Wommack KE. Novel Viral DNA Polymerases From Metagenomes Suggest Genomic Sources of Strand-Displacing Biochemical Phenotypes. Front Microbiol. 2022 Apr 21;13:858366. 

Doss RK, Palmer M, Mead DA, Hedlund BP. Functional biology and biotechnology of thermophilic viruses. Essays Biochem. 2023 Aug 11;67(4):671-684.

Palmer M, Hedlund BP, Roux S, Tsourkas PK, Doss RK, Stamereilers C, Mehta A, Dodsworth JA, Lodes M, Monsma S, Glavina Del Rio T, Schoenfeld TW, Eloe-Fadrosh EA, Mead DA. Diversity and Distribution of a Novel Genus of Hyperthermophilic Aquificae Viruses Encoding a Proof-Reading Family-A DNA Polymerase. Front Microbiol. 2020 Nov 12;11:583361. doi: 10.3389/fmicb.2020.583361.

Benzine J., Brown KM., Agans KN., Godiska R., Mire CE., Gowda K., Converse B., Geisbert TW., Mead DA., and Chander Y. (2016) Molecular diagnostic field test for point-of-care detection of Ebola virus directly from blood. J. Infect. Dis 214(3): S234-S242.

Chander Y., Koelbl J., Puckett J., Moser MJ., Klingele AJ., Liles MR., Carrias A., Mead DA., and Schoenfeld TW. (2014) A novel thermostable polymerase for RNA and DNA loop-mediated isothermal amplification (LAMP). Frontiers Microbiol 5:395.

Mead D, Monsma S, Mei B, Gowda K, Lodes M, Schoenfeld T. Functional Metagenomics of a Replicase from a Novel Hyperthermophilic Aquificales Virus. In: Charles TC, Liles MR, Sessitsch A, editors. Functional Metagenomics: Tools and Applications Switzerland: Springer; 2017. Chapter 13; p.217-242.

Moser MJ, DiFrancesco RA, Gowda K, Klingele AJ, Sugar DR, Stocki S, Mead DA, Schoenfeld TW. Thermostable DNA polymerase from a viral metagenome is a potent RT-PCR enzyme. PLoS One. 2012;7(6):e38371. doi: 10.1371/journal.pone.0038371. Epub 2012 Jun 4. PubMed PMID: 22675552; PubMed Central PMCID: PMC3366922.

Dhodda V, Godiska R, Vanwye JD, Mead D, Hochstein R, Sheets L, Vande Zande S, Niebauer C, Crawford DL, Oleksiak MF. ExCyto PCR amplification. PLoS One. 2010 Sep 8;5(9):e12629. doi: 10.1371/journal.pone.0012629. PubMed PMID: 20838619; PubMed Central PMCID: PMC2935887.

Schoenfeld T, Liles M, Wommack KE, Polson SW, Godiska R, Mead D. Functional viral metagenomics and the next generation of molecular tools. Trends Microbiol. 2010 Jan;18(1):20-9. doi: 10.1016/j.tim.2009.10.001. Epub 2009 Nov 5. Review. PubMed PMID: 19896852; PubMed Central PMCID: PMC2818347.

Schoenfeld T, Patterson M, Richardson PM, Wommack KE, Young M, Mead D. Assembly of viral metagenomes from Yellowstone hot springs. Appl Environ Microbiol. 2008 Jul;74(13):4164-74. doi: 10.1128/AEM.02598-07. Epub 2008 Apr 25. PubMed PMID: 18441115; PubMed Central PMCID: PMC2446518.

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Application notes

VariSafe™ RNAs

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Product sheets and protocols

Bolt™ Polymerase

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Thunder™ RT

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VariSafe™ RNAs

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Cod Uracil-DNA Glycosylase

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Tn5 Transposase

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CRISPR/Cas9

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CRISPR/Cas9 NLS

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EconoScript™ RT

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T4 gene 32 protein

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MS2 phage

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Take your research and development to the next level by leveraging our unmatched expertise and passion for enzymes. We look forward to being your trusted partner for current and future enzyme and molecular biology needs. Contact us today.

3220 Deming Way, Suite 160, Middleton, WI 53562

Talk to an Expert

Scientific Spotlight - Selection of Varizymes' Team

Varizymes

Yogesh Chander, PhD

Chief Technology Officer

3,800+ citations. See Google Scholar
Varizymes

Alyssa Hassinger

Research Scientist

190+ citations
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