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For rapid detection of Foot-and-Mouth disease (FMD) virus at point-of-care. FMD is a highly contagious viral disease of cloven-hoofed animals, endemic in many parts of the world. Varizymes is developing a LAMP-based diagnostic kit for detection of FMD virus at POC within 30 minutes.

Current LAMP methods can independently detect and differentiate only one target per reaction compared to 3-4 in a standard real-time PCR reaction. Varizymes’ TORCH™ Technology enables detection of up to 3 targets (DNA or RNA) in a single LAMP reaction. This technology expands upon existing LAMP primer design and does not require the use of additional primers or probes.

The RNA-guided endonuclease Cas9, associated with Type II CRISPR/Cas systems, site-specifically digests DNA using a single guide RNA (sgRNA) which it binds to direct it to the complementary sequence. Varizymes offers a unique, patent-pending version of Streptococcus pyogenes CRISPR/Cas9 nuclease with multiple NLSs for in vivo nuclear localization and a β-lactamase (Bla) for sorting of successfully transformed or transfected cells by flow cytometry (details on use conditions available
upon request).

Varizymes

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Take your research and development to the next level by leveraging our unmatched expertise and passion for enzymes. We look forward to being your trusted partner for current and future enzyme and molecular biology needs. Contact us today.

3220 Deming Way, Suite 160, Middleton, WI 53562

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Scientific Spotlight - Selection of Varizymes' Team

Varizymes

Yogesh Chander, PhD

Chief Technology Officer

3,800+ citations. See Google Scholar
Varizymes

Alyssa Hassinger

Research Scientist

190+ citations
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